Anti-CDC34抗體,細胞周期調(diào)控因子34抗體說明書產(chǎn)品介紹：Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Cooperates with the E2 UBCH5C and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin. UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Cooperates with the SCF(SKP2) E3 ligase complex to regulate cell proliferation through ubiquitination and degradation of MYBL2 and KIP1. Involved in ubiquitin conjugation and degradation of CREM isoform ICERIIgamma and ATF15 resulting in abrogation of ICERIIgamma- and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles. Involved in the regulation of the cell cycle G2/M phase through its targeting of the WEE1 kinase for ubiquitination and degradation. Also involved in the degradation of beta-catenin. Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes. 

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時4°C存儲，保質期六個月，*存儲時建議分裝為10ul以上小包裝-20°C存儲，并避免反復凍融，保質期一年。

產(chǎn)品名稱 Anti-CDC34抗體,細胞周期調(diào)控因子34抗體說明書

產(chǎn)品編號 BYK-1392R

英文名稱 CDC34
中文名稱 細胞周期調(diào)控因子34
別    名 Cdc 34; Cdc34; Cell division cycle 34; Cell division cycle 34 homolog (S. cerevisiae); Cell division cycle 34 homolog; E2 CDC34; UB2R1_HUMAN; UBC 3; UBC3; UBCH3; UBE2 R1; UBE2R1; Ubiquitin carrier protein; Ubiquitin conjugating enzyme Cdc34; Ubiquitin conjugating enzyme E2 32 kDa complementing; Ubiquitin protein ligase; Ubiquitin protein ligase R1; Ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; Ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1
研究領域 細胞生物  細胞凋亡  細胞周期蛋白  轉錄調(diào)節(jié)因子                             

抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應、產(chǎn)品應用 （具體交叉反應與產(chǎn)品應用請）

    Anti-CDC34抗體,細胞周期調(diào)控因子34抗體說明書更多優(yōu)質產(chǎn)品有：

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*受體1抗體 Anti-SSTR1
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*抑制蛋白激酶C底物抗體 Anti-AKAP12/Gravin
A2LD1蛋白抗體 Anti-A2LD1/GGACT
干燥癥SSB/La抗體 Anti-SSB/La
磷脂酰肌醇激酶PIK3-γ抗體 Anti-PIK3 gamma
核糖核蛋白抗原抗體 Anti-SSA/RO52
睪丸凋亡基因抗體 Anti-SRG11/Spata17
核因子1B抗體 Anti-NFIB/NF1B2
睪丸特異表達新基因5抗體 Anti-SRG5/SPATA12
核因子1A抗體 Anti-NFIA/NF-1